Fried's Rule Calculator (Educational Infant Reference)
Estimates infant dose (<24 months) from age in months and adult dose for academic/GPAT examination preparation.
⚠️ Educational Calculation & Clinical Safety Safeguard: EDUCATIONAL / HISTORICAL FORMULA ONLY: Neonates and infants have immature renal/hepatic clearance; never use Fried's rule for clinical prescribing. Educational calculations do not replace clinician assessment, patient-specific laboratory monitoring, or institutional prescribing protocols.
Interactive Calculator
Allowed physiological/compounding range: 1 to 24 months
Allowed physiological/compounding range: 1 to 5000 mg
Calculated Output (mg)
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Step-by-Step Mathematical Derivation & Explanation:
Validated Formula & Conversion Rules
Fried's Rule: Infant Dose = [Age (months) / 150] × Adult Dose
Worked Clinical Example
10-month-old infant, Adult Dose 300 mg: Infant Dose = (10 / 150) × 300 = 20 mg.
Rounding Rules, Assumptions & Source References
- Rounding Rule: Round to 2 decimal places for examination questions.
- Clinical Assumptions & Limitations: Validated only within the stated physiological input boundaries. For paediatric, renal (Cockcroft-Gault), and critical-care infusion calculations, always cross-check against official product labelling and institutional guidelines.
- Source References: Indian Pharmacopoeia (IP 2022), National Formulary of India (NFI), British National Formulary (BNF), and NCBI Bookshelf Clinical Pharmacology Compendia.